rel-(1R,2S)-3,3-Dimethylcyclopropane-1,2-dicarboxylic acid
cis-3,3-dimethylcyclopropane-1,2-dicarboxylic acid
CAS: 936-87-8
Molecular Formula: C7H10O4
rel-(1R,2S)-3,3-Dimethylcyclopropane-1,2-dicarboxylic acid - Names and Identifiers
rel-(1R,2S)-3,3-Dimethylcyclopropane-1,2-dicarboxylic acid - Physico-chemical Properties
| Molecular Formula | C7H10O4 |
| Molar Mass | 158.15 |
rel-(1R,2S)-3,3-Dimethylcyclopropane-1,2-dicarboxylic acid - Introduction
cis-3, 3-dimethylcyclopane-1, 2-dicarboxylic acid(cis-3) is an organic compound. It has the following properties:
1. Appearance: cis-3, 3-dimethylcyclopane-1, 2-dicarboxylic acid is colorless crystal or white solid.
2. Solubility: It is soluble in ethanol, ethyl ether and ethyl acetate, slightly soluble in water.
3. Stability: cis-3, 3-dimethylcyclopane-1, 2-dicarboxylic acid is relatively stable at room temperature, but is sensitive to moisture and light.
cis-3, the main uses of 3-dimethylcyclopane-1, 2-dicarboxylic acid are:
1. Chemical synthesis: It can be used as an intermediate in organic synthesis and used in the synthesis of other compounds.
2. Drug research: cis-3, 3-dimethylcyclopane-1, 2-dicarboxylacid has certain applications in the field of drug research, as the structural skeleton of target compounds or drug molecules.
The method of preparing cis-3, 3-dimethylcyclopane-1, 2-dicarboxylic acid includes the following steps:
1. 3,3-dimethylcyclopropane -1,2-diol is reacted with o-hydrobromoacetate to generate 3,3-dimethylcyclopropane -1,2-dimethyl ester.
2. The above intermediate is reacted with potassium tert-butyl peroxide under alkaline conditions to generate cis-3, 3-dimethylcyclopane-1, 2-dicarboxylic acid by epoxidation.
cis-3, the safety information of 3-dimethylcyclopane-1, 2-dicarboxylic acid has not been clearly reported, but as an organic acid, it may cause irritation to eyes, skin and respiratory system. Wear protective gloves, glasses and breathing apparatus during handling and use, and ensure good ventilation. Follow relevant safety procedures and precautions when using in a laboratory environment.
1. Appearance: cis-3, 3-dimethylcyclopane-1, 2-dicarboxylic acid is colorless crystal or white solid.
2. Solubility: It is soluble in ethanol, ethyl ether and ethyl acetate, slightly soluble in water.
3. Stability: cis-3, 3-dimethylcyclopane-1, 2-dicarboxylic acid is relatively stable at room temperature, but is sensitive to moisture and light.
cis-3, the main uses of 3-dimethylcyclopane-1, 2-dicarboxylic acid are:
1. Chemical synthesis: It can be used as an intermediate in organic synthesis and used in the synthesis of other compounds.
2. Drug research: cis-3, 3-dimethylcyclopane-1, 2-dicarboxylacid has certain applications in the field of drug research, as the structural skeleton of target compounds or drug molecules.
The method of preparing cis-3, 3-dimethylcyclopane-1, 2-dicarboxylic acid includes the following steps:
1. 3,3-dimethylcyclopropane -1,2-diol is reacted with o-hydrobromoacetate to generate 3,3-dimethylcyclopropane -1,2-dimethyl ester.
2. The above intermediate is reacted with potassium tert-butyl peroxide under alkaline conditions to generate cis-3, 3-dimethylcyclopane-1, 2-dicarboxylic acid by epoxidation.
cis-3, the safety information of 3-dimethylcyclopane-1, 2-dicarboxylic acid has not been clearly reported, but as an organic acid, it may cause irritation to eyes, skin and respiratory system. Wear protective gloves, glasses and breathing apparatus during handling and use, and ensure good ventilation. Follow relevant safety procedures and precautions when using in a laboratory environment.
Last Update：2024-04-09 18:58:34
